Introduction: Although modern therapies for cancer have improved life expectancy, the management of
disease and improvement of quality of life (QoL) of patients, especially managing cancer-related pain and
chronic fatigue syndrome are still limited. We demonstrate the efficacy of a combined therapy to treat cancer
patients suffering from CFS. The effects of a combined therapy in cancer patients suffering from CFS was
evaluated. NK cells were stimulated, additional tumour treatment together with targeted radiofrequency
Methods: SIXTY patients with CFS (due to suffering from any type of cancer) were recruited, (according to
the Centres for Disease Control 1994 criteria) attending an outpatient specialist CFS service for controlled
pilot study. A total of 25 participants were given oral BioBran (MGN-3-Arabinoxylane), + Oncothermia, for
six months, equivalent control group has not received this complex (BioBran + Oncothermia) treatment,
they received chemo-,radiotherapy treatment.
Results: The whole body pH status showed strong tissue acidity before the treatment, but the BioBran
group changed the tissue pH status. The most important finding was that the average of CFQ score was
significantly reduced after the treatment, and in control group the CFQ scores did not change
Conclusion: The findings support a specific therapeutic effect of the complex BioBran+ Oncothermia
therapy in CFS of cancer patients improving their QoL, enhancing NK activity in synergy.
© 2016 Published by Elsevier GmbH.